It's rare to see an American car holding its own against the Europeans on a list such as this, but we're graced with a precious few. Saleen is based in Corona, Calif., and got its start tuning Mustangs before branching out into creating its own supercars. The original Saleen S7, which was released in 2003, featured a robust 7-liter, V-8 Ford powerplant -- along the same lines as those used for NASCAR. A couple years later, Saleen decided to hunt down the Bugatti Veyron and its ilk, and updated the S7 with a pair of Garrett turbos. The twin-turbo setup was supposedly the plan all along, but Saleen decided to start (relatively) small and upgrade when the need arose. Chasing down the world's fastest cars was obviously sufficient justification for pushing this monster to the 750-horsepower mark. Saleen continued to produce this coupe in small numbers until 2009, but by then, the S7 Twin-Turbo had already made its mark.